This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.
Powerful perspectives
Industry Insight
Reflections from our CEO
Industry Insight
Pancreatic cancer – our commitment to scientific advances
Industry Insight
A bold new era in global cancer drug discovery
Industry Insight
A note from our CEO
Industry Insight
Realising the potential of autotaxin therapy in cancer
Industry Insight
PI3Kδ inhibitors offer serious promise in solid tumors
Industry Insight
Emerging therapies offer hope for uveal melanoma patients
All articles
Data & publication
Safety and clinical activity of IOA-244, a highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ), in a Phase I first in human (FIH) study (study part A)
Data & publicationIOA-244 is a non-ATP-competitive, highly-selective, tolerable phosphoinositide-3-linase delta inhibitor that directly targets solid tumors and breaks immune tolerance
Data & publicationNon-ATP competitive inhibition of PI3δ with IOA-244 shows anti-lymphoma activity
Press releaseiOnctura expands Advisory Board
Data & publicationSafety, pharmacokinetic (PK), pharmacodynamic (PD) and activity of the highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ) inhibitor IOA-244 in patients with follicular lymphoma (FL)
Data & publicationFirst-in-human (FIH) phase I study of the highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ) inhibitor IOA-244 in patients with advanced cancer
Press releaseiOnctura to present at ASCO IOA-244 showing highly promising impact on overall survival for patients with metastatic and refractory uveal melanoma
Press coverageBioWorld — IOA-244 to revive PI3K delta inhibitors?
Press releaseiOnctura to present at ASCO encouraging Phase Ib refractory uveal melanoma data for first semi-allosteric PI3Kδ inhibitor, IOA-244
Data & publicationThe role of CAF in promoting cancer cell proliferation
Data & publicationiOnctura data at AACR demonstrates unique mechanism of action for clinical stage autotaxin inhibitor IOA-289
Press releaseiOnctura data at AACR demonstrates unique mechanism of action for clinical stage autotaxin inhibitor IOA-289
Looking for media
resources?