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Safety and clinical activity of IOA-244, a highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ), in a Phase I first in human (FIH) study (study part A)

Data & Publications Bg

IOA-244 is a non-ATP-competitive, highly-selective, tolerable phosphoinositide-3-linase delta inhibitor that directly targets solid tumors and breaks immune tolerance

Data & Publications Bg

Non-ATP competitive inhibition of PI3δ with IOA-244 shows anti-lymphoma activity

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iOnctura expands Advisory Board

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Safety, pharmacokinetic (PK), pharmacodynamic (PD) and activity of the highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ) inhibitor IOA-244 in patients with follicular lymphoma (FL)

Data & Publications Bg

First-in-human (FIH) phase I study of the highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ) inhibitor IOA-244 in patients with advanced cancer

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iOnctura to present at ASCO IOA-244 showing highly promising impact on overall survival for patients with metastatic and refractory uveal melanoma

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BioWorld — IOA-244 to revive PI3K delta inhibitors?

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iOnctura to present at ASCO encouraging Phase Ib refractory uveal melanoma data for first semi-allosteric PI3Kδ inhibitor, IOA-244

Data & Publications Bg

The role of CAF in promoting cancer cell proliferation

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iOnctura data at AACR demonstrates unique mechanism of action for clinical stage autotaxin inhibitor IOA-289

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iOnctura data at AACR demonstrates unique mechanism of action for clinical stage autotaxin inhibitor IOA-289

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