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Powerful perspectives
Industry Insight
Reflections from our CEO
Industry Insight
Pancreatic cancer – our commitment to scientific advances
Industry Insight
A bold new era in global cancer drug discovery
Industry Insight
A note from our CEO
Industry Insight
Realising the potential of autotaxin therapy in cancer
Industry Insight
PI3Kδ inhibitors offer serious promise in solid tumors
Industry Insight
Emerging therapies offer hope for uveal melanoma patients
All articles
Data & publication
Characterization and translational development of IOA-289, a novel autotaxin inhibitor for the treatment of solid tumors
Press releaseiOnctura to present research at leading scientific conferences in June 2023
Press releasePeer-reviewed translational research paves the way for first-in-class autotaxin inhibitor IOA-289 in cancer
Press releaseiOnctura expands pipeline and receives development grant from Health Holland and KWF
Data & publicationIOA-244 is a non–ATP-competitive, highly selective, tolerable PI3K delta inhibitor that targets solid tumors and breaks immune tolerance
Press releaseiOnctura awarded UK’s MHRA innovation passport for entry into innovative licensing and access pathway (ILAP)
Data & publicationLong-term safety evaluation of roginolisib (formerly IOA-244), a highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ), in a Phase I First in Human (FIH) study
Press releaseiOnctura announces publication of pioneering research describing the unique biological features of roginolisib
Data & publicationCharacterization of the non-ATP competitive PI3Kδ inhibitor IOA-244 in lymphoma models: from single agent to combination screen and clinical investigation
Press releaseiOnctura provides development update on first-in-class semi-allosteric PI3Kδ inhibitor program
Press releaseiOnctura awarded EUR17.5 million funding from the EIC accelerator for clinical development of novel pancreatic cancer therapy
Press releaseiOnctura initiates Phase Ib pancreatic cancer trial of next-generation autotaxin inhibitor IOA-289
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