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Powerful perspectives
Industry Insight
Pancreatic cancer – our commitment to scientific advances
Industry Insight
A bold new era in global cancer drug discovery
Industry Insight
A note from our CEO
Industry Insight
Realising the potential of autotaxin therapy in cancer
Industry Insight
PI3Kδ inhibitors offer serious promise in solid tumors
Industry Insight
Emerging therapies offer hope for uveal melanoma patients
All articles
Data & publication
Pancreatic CAF-derived Autotaxin (ATX) drives autocrine CTGF expression to modulate pro-tumorigenic signaling
Press coverageDrug Target Review – Biotech leader champions targeted cancer treatments and diversity
Data & publicationHigh levels of autotaxin and lysophosphatidic acid predict poor outcome in treatment of resectable gastric carcinoma
Data & publicationRoginolisib (IOA-244), a first oral allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3Kδ) in patients with metastatic uveal melanoma
Press coverageMedNous – Small company, big theme: How iOnctura is pursuing drug resistance
Press releaseiOnctura announces expansion of roginolisib clinical trial program to NSCLC
Press coverageEndpoints News – iOnctura raises €80M to advance early-stage rare eye cancer treatment
Press coverageFirstWord Pharma – With fresh €80M in hand, iOnctura looks to chart new PI3K path
Press release€80 million Series B financing to progress pipeline through Phase II trials
Data & publicationRoginolisib: an oral, highly selective and allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3kδ) in patients with uveal melanoma and advanced cancers
Press releaseUS FDA grants orphan drug designation for iOnctura’s first-in-class autotaxin cancer therapy
Data & publicationThe highly selective and oral phosphoinositide 3-kinase delta (PI3K-δ) inhibitor roginolisib induces apoptosis in mesothelioma cells and increases immune effector cell composition
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