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Pancreatic CAF-derived Autotaxin (ATX) drives autocrine CTGF expression to modulate pro-tumorigenic signaling

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Drug Target Review – Biotech leader champions targeted cancer treatments and diversity

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High levels of autotaxin and lysophosphatidic acid predict poor outcome in treatment of resectable gastric carcinoma

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Roginolisib (IOA-244), a first oral allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3Kδ) in patients with metastatic uveal melanoma

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MedNous – Small company, big theme: How iOnctura is pursuing drug resistance

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iOnctura announces expansion of roginolisib clinical trial program to NSCLC

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Endpoints News – iOnctura raises €80M to advance early-stage rare eye cancer treatment

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FirstWord Pharma – With fresh €80M in hand, iOnctura looks to chart new PI3K path

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€80 million Series B financing to progress pipeline through Phase II trials

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Roginolisib: an oral, highly selective and allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3kδ) in patients with uveal melanoma and advanced cancers

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US FDA grants orphan drug designation for iOnctura’s first-in-class autotaxin cancer therapy

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The highly selective and oral phosphoinositide 3-kinase delta (PI3K-δ) inhibitor roginolisib induces apoptosis in mesothelioma cells and increases immune effector cell composition

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