Our purpose
Giving every cancer sufferer hope. Every day, we work towards delivering treatments that have low toxicity and are gentle on the body, yet powerful in disrupting and inhibiting tumors.
Our mission is to develop high impact, low disruption therapies that extend healthspan for patients. We do this by interrogating first-in-class mechanisms that disrupt the dynamic interplay at the heart of the tumor-stroma-immune interface.
Our culture
Values-driven collaboration
Our working culture fosters innovation and respect.
We believe in empowering our team, encouraging open communication, and valuing diverse perspectives.
This inclusive environment drives our success,
enabling us to achieve our goals and make a positive impact together.
01 Pioneering
We are always pushing boundaries and challenging the status quo wherever possible, so as to to deliver novel solutions that push our industry forward.
02 Sustainable
We relentlessly prioritise creative resourcing, cultivate an organic culture and implement innovative processes to ensure sustainable practices and long-term responsibility.
03 Agile
We have a collaborative spirit, balancing internal and external resourcing to achieve maximal impact with the highest degree of confidence.
04 Responsible
We uphold honesty, integrity, and respect in all interactions with our patients, partners and other stakeholders; ensuring ethical and responsible practices, at all times.
Our leadership
Meet the people
making it happen.
Exec team
Driving us towards our mission every day, our diverse and expert exec team lead our corporate operations across our key geographies.
Catherine Pickering Co-Founder, CEO
Catherine Pickering is a highly respected and ambitious life sciences leader. As CEO and Co-Founder of iOnctura, Catherine has built iOnctura as a lean by highly efficient drug development company, supported by more than 15 team members including research scientists, medical professionals and business leaders. Since the company’s inception in 2017, she has raised over €100M in private financing, to progress iOnctura’s pipeline of precision oral small molecules, securing two programmes into mid-stage clinical development and in-licensing another small molecule program against a key cancer target.
She is scientifically curious and is driven by her lifelong commitment to oncology research, striving to bring to market ground-breaking therapies which have the potential to improve – and ultimately extend – healthspan for patients.
Prior to launching iOnctura, Catherine led the global oncology and immuno-oncology licensing and business development function at Merck KGaA and was a core member of the global oncology franchise leadership team. In this position she was an accomplished deal maker, closing several deals per annum including negotiating the biggest upfront out-licensing deal payment in the industry at the time.
Catherine holds a PhD in Medicinal Chemistry from the UK’s Institute of Cancer Research and an MBA from Henley Business School.
Lars van Der Veen Co-Founder, CSO
Lars holds a PhD in chemistry. He is a medicinal chemist with over 20 years of experience in biopharma R&D and delivered multiple clinical candidates and lead compounds for different therapeutic areas including oncology.
Prior to founding iOnctura he has held various positions in project management and project leadership spanning early discovery up to commercial products and dealing with both biologics and small molecules. Lars has previously worked at Solvay Pharmaceuticals, Organon, Boehringer-Ingelheim and Merck.
Michael Lahn CMO
Michael joined iOnctura as Chief Medical Officer in 2019 after 20 years of industry experience at Eli Lilly and Company, AstraZeneca and Incyte Corporation.
In his career Michael contributed to the development of several new molecular entities, such as small molecule inhibitors (including the ALK5 inhibitor galunisertib and the registration of osimertinib in NSCLC), large molecules, antisense oligonucleotides and vaccines. Michael is passionate about developing novel therapies in cancer and mentoring colleagues in clinical drug development.
David Seeberger CFO
David joined iOnctura as VP Finance in 2021 and has extensive experience in publicly-listed growth-oriented biotech and medtech companies.
Before taking charge of global finance operations at iOnctura, he served as VP Head of Finance Europe at NASDAQ listed bluebird bio, and held senior financial positions at Aegerion Pharmaceuticals, InterMune Corporation and Stryker Corporation.
Paul Beresford SVP New Product Planning & Business Transformation
Paul has over 25 years of experience in the biopharmaceuticals industry, including Bayer, Shire and Blueprint Medicines. Paul has launched products in various therapeutic areas, including oncology and rare diseases, globally and nationally. Having led the European build-out for a biotech and driving the development of global product life-cycle strategies for complex portfolios, Paul has expertise in cross-functional leadership and commercialisation.
At iOnctura, Paul is responsible for Operations and New Product Planning.
Kiran Roest VP Corporate Communications & Development
Kiran holds a PhD in viral-induced oncogenesis and has 15 years experience in life-sciences commercialisation, business development, strategy, consulting and project and team management.
In her career Kiran has led teams within a number of organisations to get new products to market. At iOnctura she leads on commercial efforts including strategic planning, commercial forecasting, launch strategies, market research and corporate communications.
Giusy Di Conza Head of Research
Giusy holds a PhD in endocrinological cancers. She joined iOnctura as Head of Research in 2022 with over 12 years of experience in onco-immunology and tumor-stroma interactions.
During her career, Giusy has furthered understanding of the molecular and biological interactions that occur within the tumor microenvironment, has uncovered novel preclinical targets, and published over 30 research articles. She is passionate about developing promising cancer therapies that aim to have direct impacts on patients’ lives.
BOARD
Steering us through a complex landscape, our Board provides strategic guidance and financial oversight, ensuring we’re always working towards our vision.
Joanna Horobin Chair
Joanna Horobin M.B., Ch.B. is an accomplished drug developer and biotech leader with over 35 years of experience in the pharmaceutical and biotech sector. As well as serving as the Chair of iOnctura’s Board, Dr. Horobin is also a Non-Executive Director on the board of Liquidia Technologies (LQDA: Nasdaq). Joanna has held multiple C-suite roles in biotech companies in the USA, most recently as the Chief Medical Officer at Idera Pharmaceuticals Inc. (NASDAQ, IDRA) and was also the CEO of Syndax Pharmaceuticals (NASDAQ, SNDX). Joanna led a joint venture between Rhone Poulenc and Chugai to develop and launch Chugai’s gCSF product Granocyte in Europe and, as VP Oncology, launched Rhone Poulenc Rorer (now Sanofi) as a major player in oncology with the global launch of Taxotere.
After gaining her medical qualifications from the University of Manchester’s Medical School in the United Kingdom, Dr. Horobin initially pursued a career as a General Practitioner, gaining membership of the Royal College of General Practitioners and practicing as a GP in London.
Catherine Pickering Co-Founder, CEO
Catherine Pickering is a highly respected and ambitious life sciences leader. As CEO and Co-Founder of iOnctura, Catherine has built iOnctura as a lean by highly efficient drug development company, supported by more than 15 team members including research scientists, medical professionals and business leaders. Since the company’s inception in 2017, she has raised over €100M in private financing, to progress iOnctura’s pipeline of precision oral small molecules, securing two programmes into mid-stage clinical development and in-licensing another small molecule program against a key cancer target.
She is scientifically curious and is driven by her lifelong commitment to oncology research, striving to bring to market ground-breaking therapies which have the potential to improve – and ultimately extend – healthspan for patients.
Prior to launching iOnctura, Catherine led the global oncology and immuno-oncology licensing and business development function at Merck KGaA and was a core member of the global oncology franchise leadership team. In this position she was an accomplished deal maker, closing several deals per annum including negotiating the biggest upfront out-licensing deal payment in the industry at the time.
Catherine holds a PhD in Medicinal Chemistry from the UK’s Institute of Cancer Research and an MBA from Henley Business School.
Hakan Goker Non-Executive Director
Hakan Goker (Ph.D.) is a senior investment director at Merck Ventures, corporate venture arm of the biopharmaceutical division of Merck KGaA, Darmstadt, Germany. Hakan joined Merck Ventures in 2013 and previously was investing as a partner at Aescap Venture and prior to that at Atlas Venture.
Since 2006, Hakan was instrumental in the creation, financing, and strategy of multiple biotechnology companies globally including Asceneuron (CH), Orphazyme (DK), Nimbus Discovery (US), F Star (NL), Bicycle Therapeutics (UK) and Nitec now Horizon Pharma (CH/US). Hakan received his PhD in cancer biology from the Institute of Cancer Research/ University of London and continued his scientific career with post-doctoral work at the Breakthrough Breast Cancer Centre/Royal Marsden Hospital.
He gained his BSc Honours, from University College London. Hakan is a board member of Asceneuron, Forendo Pharma, Raze Therapeutics, Tocopherx, Synaffix, and Storm Therapeutics.
Thijs Cohen Tervaert Non-Executive Director
Thijs Cohen Tervaert is a Partner at Inkef and has been with Inkef since 2016.
Prior to Inkef, Thijs was a strategy consultant at the Boston Consulting Group with a focus on health care and technology. Thijs worked on projects advising clients in the pharmaceutical industry, health insurers and large hospital systems. Thijs helped to establish the Amsterdam Health and Technology Institute in 2014.
Thijs is a medical doctor and graduated at Leiden University. He has also co-authored several scientific papers in the field of diabetes. Thijs currently also serves on the board of TargED BioPharmaceuticals, Calypso Biotech, Audion Therapeutics, ViCentra, Aidence and Castor.
Laurent Massuyeau Non-Executive Director
Laurent is Owner and President of iQone Healthcare Group, a company specialized in building and managing dedicated pharmaceutical sales operations in Europe and selected emerging markets. Laurent was formerly Head of licensing oncology global business development with Merck Serono SA in Geneva, from 2009 until 2011, when he left Merck Serono to run his own company late 2011.
Prior to this, he held several general management and corporate positions in the pharmaceutical industry. Laurent spent several years with Eli Lilly, where he held cross-functional responsibilities at local level in sales and marketing (Zyprexa, Regional Marketing Manager Europe, Middle East, Africa, Sales Manager in the US, Business Unit Director (France) and at a corporate level (Corporate Strategy Manager).
Following this, he became Executive Director European Commercial Operations for Idenix (a US biotech company owned by Novartis) and subsequently, Head of Specialty Franchises for Novartis France (transplantation, ophthalmology, neurosciences, infectious diseases, mature products).
Education: Doctorate in veterinary medicine and an MBA from INSEAD.
Roel Bulthuis Non-Executive Director
Alice Renard Non-Executive Director
Advisory Board
Providing counsel and consultation, our seasoned and wide-ranging advisory board provide invaluable industry advice and insight.
Our History
Looking back on
our journey so far…
2017
- Seed: €2.1m — company foundation
2019
- Preclinical presentation of IOA-244 at AACR
2020
- Series A: €20.1m
- First in human dose study in solid tumor patients started for I0A-244
2021
- IOA-289 in healthy volunteer study
- IOA-244 completes dose escalation and starts expansion in uveal melanoma
2022
- Start of the Phase 1b study of IOA-289 in pancreatic cancer
- EIC Accelerator Fund: €17.5m
2023
- ILAP Passport for IOA-244 assigned by the UK MHRA
- IND clearance for IOA-244 in the US
2024
- US FDA approves ODD for IOA-289 in pancreatic cancer
- Series B: €80m
Our investors
Purposeful partnerships
Finding investors aligned with our vision ensures sustainable growth. Shared values foster trust, enabling strategic decisions that drive innovation and impact, ultimately shaping a brighter future — for our business, but most importantly, our patients — together.
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